期刊 健择联合伽玛刀与健择单独化疗治疗晚期胰腺癌的疗效比较  被引量:2

Efficacy of Gemcitabine Combined with Gamma Rays Radiotherapy and Gemcitabine Alone for Advanced Pancreatic Cancer

作  者:谭晶[1] 卢永刚[1] 梁颖[1] 王昭辉[1] 

机构地区:[1]昆明医学院第二附属医院外一科

出  处:《昆明医学院学报》2008年第3期144-146,共3页Journal of Kunming Medical University

Efficacy of Gemcitabine Combined with Gamma Rays Radiotherapy and Gemcitabine Alone for Advanced Pancreatic Cancer

摘  要:目的观察健择联合伽玛刀与健择单独化疗治疗晚期胰腺癌的近期疗效和临床受益反应.方法经病理组织学或细胞学证实的50例胰腺癌患者,随机分为健择联合伽玛刀组和健择单独化疗组,每组25例.结果完成综合治疗后3个月CT检查,健择联合伽玛刀组CR7例(28%),PR9例(36%),NC7例(28%),PD2例(8%),有效率(CR+PR)64%(16/25),健择单独化疗组CR3例(12%),PR6例(24%),NC13例(52%),PD3例(12%),有效率(CR+PR)36%(9/25),两组有效率差异有统计学意义(P<0.05);健择联合伽玛刀组CBR为20/25(80%);健择单独化疗组CBR为13/25(52%),两组相比差异有统计学意义(P<0.05).结论健择联合伽玛刀比健择单独治疗晚期胰腺癌具有较好的耐受性和疗效.

Objective To compare the efficacy of gemcitabine combined with gamma rays radiotherapy and gemeitabine alone for treatment of advanced pancreatic cancer. Methods The histologic or cytologic confirmed 50 cases of pancreatic cancer were randomly divided into control gemcitabine combined with gamma rays radiotherapy with gemcitabine alone group treatment, each 25 Cases. Results The general remission rates (CR+PR) were 64% in gemcitabine combined with gamma rays radiotherapy group and 36% in gemeitabine alone group respectively. There was significant statistical diference between two group (P 〈 0.05). Conclusion Gemcitabine combined with gamma rays radiotherapy is better than gemcitabine alone in feasibality and effectiveness.

关 键 词:健择 伽玛刀 胰腺肿瘤 

Gemcitabine  Gamma rays  Pancreatic neoplasms 

分 类 号:R730.53[医药卫生—肿瘤]

 

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