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期刊Ikaros isoforms:The saga continues
世界生物化学杂志英文版电子版)》2011年第6期140-145,共6页Laura A Perez-Casellas Aleksandar Savic Sinisa Dovat 
Supported by (in part) An R01 HL095120 grant,a St.Baldrick’s Foundation Career Development Award,the Four Diamonds Fund of the Pennsylvania State University,College of Medicine,and the John Wawrynovic Leukemia Research Scholar Endowment (SD)
Through alternate splicing,the Ikaros gene produces multiple proteins.Ikaros is essential for normal hematopoiesis and possesses tumor suppressor activity.Ikaros isoforms interact to form dimers and potentially multim...显示全部
关键词:IKAROS Chromatin Pericentromeric TRANSCRIPTION IK-H LEUKEMIA γ satellite 
期刊Last decade update for three-finger toxins: Newly emerging structures and biological activities
世界生物化学杂志英文版电子版)》2019年第1期17-27,共11页Yuri N Utkin 
Supported by The Russian Foundation for Basic Research,No.18-04-01075 and 18-54-00031
Three-finger toxins(TFTs) comprise one of largest families of snake venom toxins. While they are principal to and the most toxic components of the venoms of the Elapidae snake family, their presence has also been dete...显示全部
关键词:Three-finger TOXINS SNAKE VENOM Structure BIOLOGICAL activity 
期刊Editorial Board
世界生物化学杂志英文版电子版)》2013年第4期73-76,共4页
2009-2013The World Journal of Biological Chemistry Editorial Board consists of 529 members,representing a team of worldwide experts in biochemistry and molecular biology.They are from 40 countries,including Argentina(...显示全部
关键词:BIOCHEMISTRY representing AUSTRALIA Brazil Chile REPUBLIC FINLAND Israel CANADA Xiong 
期刊Rethinking quasispecies theory: From fittest type to cooperative consortia
世界生物化学杂志英文版电子版)》2013年第4期79-90,共12页Luis P Villarreal Guenther Witzany 
Recent investigations surprisingly indicate that single RNA "stem-loops" operate solely by chemical laws that act without selective forces, and in contrast, self-ligated consortia of RNA stem-loops operate b...显示全部
关键词:QUASISPECIES RNA stem-loops INFECTIOUS AGENTS COOPERATIVE interactions Evolution 
期刊Cathepsins mediate tumor metastasis被引量:1
世界生物化学杂志英文版电子版)》2013年第4期91-101,共11页Gong-Jun Tan Zheng-Ke Peng Jin-Ping Lu Fa-Qing Tang 
Supported by National Natural Science Foundation of China,No.81071718,No.81000881,No.81372282 and No.30973400;Fundamental Research Funds for the Central Universities,No.21611612;Guangdong Natural Science Foundation,No.S2013010013360;the Foundation of State Key Laboratory of Oncology in South China,No.HN2011-04
Cathepsins are highly expressed in various human cancers, associated with tumor metastasis. It is superfamily, concluding A, B, C, D, E, F, G, H, L, K, O, S, V, and W family members. As a group of lysosomal proteinase...显示全部
关键词:CATHEPSIN TUMOR METASTASIS MECHANISM 
期刊Lipidomic mass spectrometry and its application in neuroscience
世界生物化学杂志英文版电子版)》2013年第4期102-110,共9页Mabel Enriquez-Algeciras Sanjoy K Bhattacharya 
Central and peripheral nervous systems are lipid rich tissues. Lipids, in the context of lipid-protein complexes, surround neurons and provide electrical insulation for transmission of signals allowing neurons to rema...显示全部
关键词:Mass SPECTROMETRY LIPIDOMICS PHOSPHOLIPIDS SERIAL signaling NEUROSCIENCE 
期刊Adaptive and maladaptive expression of the mRNA regulatory protein HuR被引量:1
世界生物化学杂志英文版电子版)》2013年第4期111-118,共8页Suman Govindaraju Beth S Lee 
The RNA-binding proteins involved in regulation of mRNA post-transcriptional processing and translation control the fates of thousands of mRNA transcripts and basic cellular processes. The best studied of these, HuR, ...显示全部
关键词:HUR RNA BINDING PROTEINS TRANSCRIPTION RNA STABILITY Translation Protein STABILITY Cell stress MicroRNAs Cancer 
期刊Effect of alcohol exposure on hepatic superoxide generation and hepcidin expression被引量:1
世界生物化学杂志英文版电子版)》2013年第4期119-130,共12页Duygu Dee Harrison-Findik Sizhao Lu Emily M Zmijewski Jocelyn Jones Matthew C Zimmerman 
Supported by Grant to Harrison-Findik DD,No.NIH R01AA017738;University of Nebraska Medical Center Undergraduate Scholarship to Lu S EPR spectroscopy studies were conducted in the EPR Core Facility,which is supported by the University of Nebraska-Lincoln Redox Biology Center,No.NIH 1 P30 GM103335
AIM: To understand the role of mitochondrial-produced superoxide(O 2 ?) in the regulation of iron-regulatory hormone, hepcidin by alcohol in the liver. METHODS: For alcohol experiments, manganese superoxide dismutase ...显示全部
关键词:HEPCIDIN ALCOHOL Iron Superoxide Superoxide DISMUTASE Liver MITOCHONDRIA MANGANESE superoxide DISMUTASE Electron PARAMAGNETIC resonance 
期刊High-density lipoprotein endocytosis in endothelial cells
世界生物化学杂志英文版电子版)》2013年第4期131-140,共10页Stefanie Fruhwürth Margit Pavelka Robert Bittman Werner J Kovacs Katharina M Walter Clemens Rhrl Herbert Stangl 
Supported by the Austrian Science Fund,No.P20116-B13 and No.P22838-B13
AIM: To describe the way stations of high-density lipoprotein(HDL) uptake and its lipid exchange in endothelial cells in vitro and in vivo. METHODS: A combination of fluorescence microscopy using novel fluorescent cho...显示全部
关键词:High-density LIPOPROTEIN ENDOCYTOSIS ENDOTHELIUM HUMAN umbilical vein ENDOTHELIAL CELLS HUMAN coronary artery ENDOTHELIAL CELLS Cholesterol 
期刊Changes in aminoacidergic and monoaminergic neurotransmission in the hippocampus and amygdala of rats after ayahuasca ingestion
世界生物化学杂志英文版电子版)》2013年第4期141-147,共7页Eduardo Ferreira de Castro-Neto Rafael Henrique da Cunha Dartiu Xavier da Silveira Mauricio Yonamine Telma Luciana Furtado Gouveia Esper Abr o Cavalheiro Débora Amado Maria da Gra a Naffah-Mazzacoratti 
Supported by Funda o de Amparo a Pesquisa do Estado de S o Paulo;Coordena o de Aperfei oamento de Pessoal de Nível Superior;Conselho Nacional de Desenvolvimento Científico e Tecnológico;Instituto Nacional de Neurociência Translacional
AIM: To evaluate changes in neurotransmission induced by a psychoactive beverage ayahuasca in the hippocampus and amygdala of naive rats. METHODS: The level of monoamines, their main metabolites and amino acid neurotr...显示全部
关键词:Ayahuasca AMINO ACIDS MONOAMINES HIPPOCAMPUS AMYGDALA 
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