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期刊The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53.
《Cell Cycle》St Clair S;Manfredi JJ
The cdc25C gene has been shown to be a novel target for transcriptional downregulation by p53. Two independent mechanisms contribute to the p53-dependent repression of the cdc25C gene. First, an element in the cdc25C ...显示全部
关键词:Animals Cell Cycle Proteins Humans Models  Genetic Promoter Regions (Genetics) Repressor Proteins Research Support  N.I.H.  Extramural Research Support  Non-U.S. Gov't Transcription  Genetic Tumor Suppressor Protein p53 cdc25 Phosphatase 
期刊A New Clinical HIFU System (Teleson II).
《AIP Conference Proceedings》Yixin Ma[1];Symonds-Tayler, Richard[1];Rivens, Ian H.[1];ter Haar, Gail R.[1]
Previous clinical trials with our first prototype HIFU system (Teleson I) for the treatment of liver tumors, demonstrated a major challenge to be treatment of those tumors located behind the ribs. We have designed a n...显示全部
关键词:IMAGING systems in medicine CLINICAL trials HEPATOMA LIVER -- Tumors TRANSDUCERS  Biomedical SIGNAL generators TREATMENT 
期刊Haemopoietic growth factors significantly improve the mitotic index andchromosome quality in cytogenetic cultures of myeloid neoplasia.
《Genes, Chromosomes and Cancer》Earle,VL; Ross,F; Fisher,A; Strike,P; Berrington,S; Chiecchio,L; Cabanas,ED;Washbourne,R; Watts,K; Grand,F
Haemopoietic growth factors stimulate bone marrow cell division,differentiation, and survival in vivo. We have investigated the use of recombinant humanhaemopoietic growth factors in vitro to improve cytogenetic cultu...显示全部
关键词:Growth Substances  Chromosomes  Neoplasms  Median Statistical Measurement 
期刊Role of IL-21 in immune-regulation and tumor immunotherapy.
《Cancer Immunology, Immunotherapy》di-Carlo,E; de-Totero,D; Piazza,T; Fabbi,M; Ferrini,S
IL-21, the most recently discovered member of the IL-2 cytokine family, is anattractive subject for research due to its involvement in experimental models of autoimmunity, itsability to down-regulate IgE production, a...显示全部
关键词:Autoimmunity  Immunotherapy  Interleukins  Neoplasms 
期刊DESMOPLASTIC MELANOMA: THE ROLE OF RADIOTHERAPY IN IMPROVING LOCAL CONTROL.
《Australian & New Zealand Journal of Surgery》Foote, Matthew C.[1]&Email: mattfoote_1@hotmail.com;Burmeister, Bryan[1];Burmeister, Elizabeth[1];Bayley, Gerard[1];Smithers, B. Mark[1]
Background: Desmoplastic melanoma (DM) is a rare subtype of cutaneous malignant melanoma reported to have a high local recurrence rate with surgical excision alone. The incidence of regional and distant metastasis is ...显示全部
关键词:MELANOMA RADIOTHERAPY HISTOLOGY  Pathological EXCISION (Surgery) TUMORS -- Growth 
期刊A Case Report of Pathologically Complete Response of a Huge Rectal Cancer after Systemic Chemotherapy with mFOLFOX6
《Japanese Journal of Clinical Oncology》Kae Okoshi[1]; Satoshi Nagayama[1]; Moritoshi Furu[2]; Yukiko Mori[1]; Akihiko Yoshizawa[3]; Junya Toguchida[2][4];Yoshiharu Sakai[1]
A 54-year-old man was referred to our hospital because of ahuge, unresectable rectal cancer occupying his entire pelvicspace with a solitary liver metastasis. He had undergone a laparotomyfor surgical resection, but e...显示全部
关键词:Neoplasms 
期刊Retrospective Study on Home Care for Patients with Hematologic Malignancies
《Japanese Journal of Clinical Oncology》Yuko Kodama[1]; Morihito Takita[1]; Shohei Kawagoe[2]; Satoshi Hirahara[3]; Yukihiro Kimura[4]; Shigeru Onozawa[5]; Tadashi Wada[2]; Kazushi Nakano[6]; Masahiro Kami[1]; Tomoko Matsumura[1];Koichiro Yuji[7]
Objective: There is a lack of sufficient information on the employmentof home care for the treatment of hematologic malignancies. Methods: We provided home care to 580 patients from 1 January through31 October 200...显示全部
关键词:Neoplasms 
期刊Low-dose continuous 5-fluorouracil infusion stimulates VEGF-A-mediated angiogenesis
《Acta Oncologica》Per Albertsson[a][b]; Bo Lennernäs[a]; Klas Norrby[c]
Background. Tumor growth is angiogenesis-dependent. Animal studies have demonstrated that frequent administration of chemotherapeutics may have marked antiangiogenic effects and improved antitumor effects, with less s...显示全部
关键词:Neoplasms 
期刊Long-term Prognostic Assessment of 185 Newly Diagnosed Gliomas—Grade III Glioma Showed Prognosis Comparable to That of Grade II Glioma
《Japanese Journal of Clinical Oncology》Chie Shinohara[1]; Yoshihiro Muragaki[1][2]; Takashi Maruyama[1]; Satoru Shimizu[3]; Masahiko Tanaka[1]; Yuichi Kubota[1]; Mitsuteru Oikawa[1]; Ryoichi Nakamura[2]; Hiroshi Iseki[1][2]; Osami Kubo[1]; Kintomo Takakura[2];Tomokatsu Hori[1]
Objective: We evaluated the prognoses of newly diagnosed gliomas throughWHO Grades II, III and IV to assess the overall tendency oftreatment results for glioma in our institute. Furthermore,statistical analysis was pe...显示全部
关键词:Neoplasms 
期刊Does ER-βcx Really Have No Clinical Importance in Tamoxifen-Treated Breast Cancer Patients?
《Journal of Clinical Oncology》Carlo Palmieri, Ondrej Gojis, Bharath Rudraraju, and Susan Cleator
关键词:Neoplasms 
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